Vardenafil and Weaning from Inhaled Nitric Oxide: Effect on Pulmonary Hypertension in ARDS
نویسندگان
چکیده
منابع مشابه
Weaning strategy with inhaled nitric oxide treatment in persistent pulmonary hypertension of the newborn.
AIM To determine if infants who had become dependent on inhaled nitric oxide treatment could be successfully weaned off it if FIO2 was increased briefly during withdrawal. METHODS Sixteen infants admitted for conditions associated with increased pulmonary vascular resistance responded well to inhaled nitric oxide treatment with a significant increase in PaO2 (maximum inhaled nitric oxide give...
متن کاملInhaled nitric oxide in persistent pulmonary hypertension of the newborn.
Nitric oxide (NO) has vasodilatory effects on the pulmonary vasculature in adults and animals. We examined the effects on systemic oxygenation and blood pressure of inhaling up to 80 parts per million by volume of NO at FiO2 0.9 for up to 30 minutes by 6 infants with persistent pulmonary hypertension of the newborn (PPHN). In all infants this treatment rapidly and significantly increased preduc...
متن کاملPulmonary Hypertension in Neonates: Inhaled Nitric Oxide vs Epoprostenol (Flolan)
J Lung Pulm Respir Res 2016, 3(3): 00082 selectively targets pulmonary vessels, causing a potent and sustained vasodilatation, and therefore increasing pulmonary blood flow [2]. After diffusion across the alveolar capillary membrane, the iNO is absorbed by subjacent smooth muscles of the pulmonary vasculature to activate soluble guanylate cyclase, which is responsible for conversion of GTP to c...
متن کاملOne-year continuous inhaled nitric oxide for primary pulmonary hypertension.
We describe a case of long-term administration of nitric oxide (NO) in a 32-year-old man who was admitted with exertional dyspnea and anasarca. A diagnosis of primary pulmonary hypertension was made. An acute vasodilator trial with inhaled NO showed a 5% reduction of the mean pulmonary artery pressure. Long-term NO inhalation therapy was initiated. Twenty days later, the dyspnea improved, the a...
متن کاملEfficacy of inhaled nitric oxide in patients with severe ARDS.
STUDY OBJECTIVE To investigate the initial and long-term effect of nitric oxide (NO) inhalation in patients with severe acute respiratory distress syndrome (ARDS). DESIGN Retrospective, clinical study. SETTING University surgical ICU. PATIENTS Eighty-seven patients with severe ARDS. INTERVENTIONS AND MEASUREMENTS Thirty of 87 patients with ARDS inhaled low concentrations of NO for more ...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 2007
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x0703500113